Pijus Kumar Sasmal
Professor
| Ph. D. | IISc, Bangalore, 2010 |
| Postdoctoral Research | Marburg University, Germany, 2010 – 2012 |
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Rutgers University, USA, 2012 – 2014 |
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Princeton University, USA, 2014 – 2015 |
| Assistant Professor | Jawaharlal Nehru University, 2015 – 2025 |
| Professor | University of Hyderabad, 2025 - Present |
Phone: +91- 40- 23134800, E-mail: pijussasmal@uohyd.ac.in
Research Interests
Keywords: Bioinorganic Chemistry; Chemical Biology; Medicinal Inorganic Chemistry; Anticancer and Antimicrobial Metallodrugs; Bioorthogonal Catalysis; Biosensors
Our research group operates at the interface of chemistry and biology, with a focus on the design and synthesis of metal-based complexes for applications in chemical biology and medicinal therapeutics. We aim to leverage the unique properties of metal ions and coordination chemistry to develop innovative tools for molecular sensing, disease diagnosis, and targeted therapy.
Our current research interests include:
Our research group operates at the interface of chemistry and biology, with a focus on the design and synthesis of metal-based complexes for applications in chemical biology and medicinal therapeutics. We aim to leverage the unique properties of metal ions and coordination chemistry to develop innovative tools for molecular sensing, disease diagnosis, and targeted therapy.
Our current research interests include:
- Designing targeted metal-based complexes for cancer therapy
- Developing metal-based diagnostic and therapeutic agents to combat antimicrobial resistance
- Tailoring metal-catalyzed bioorthogonal reactions within living cells
- Designing metal-based sensing probes for the detection of biologically relevant molecules
Selected Publications
- Harnessing the Power of Iridium AIEgens for NAD(P)H Detection in Aqueous Medium and Living Cells; Ajay Gupta, Aryan Gautam, Smaranika Patra, Amit Kunwar and Pijus K. Sasmal, Chem. Commun. 2025, 61, 7305–7308.
- Eradication of Antibiotic-Resistant Gram-Positive Bacteria and Biofilms by Rationally Designed AIE-Active Iridium(III) Complexes Derived from Cyclometalating 2-Phenylquinoline and Ancillary Bipyridyl Ligands, Aryan Gautam and Pijus K. Sasmal, Inorg. Chem. 2025, 64, 2905–2918.
- Multifunctional Iridium(III)-Platinum(IV) Conjugates as Potent Anticancer Theranostic Agents, Ajay Gupta, Abhishek Kumar Pandey, Titas Mondal, Jaydeep Bhattacharya and Pijus K. Sasmal, J. Med. Chem. 2023, 66, 8687–8704.
- Mitochondria-Targeted Photoactivatable Real-Time Monitoring of a Controlled Drug Delivery Platform, Neelu Singh, Ajay Gupta, Puja Prasad, Raj Kumar Sah, Arvind Singh, Sunil Kumar, Shailja Singh, Shalini Gupta and Pijus K. Sasmal, J. Med. Chem. 2021, 64, 17813–17823.
- Iridium-Triggered Allylcarbamate Uncaging in Living Cells, Neelu Singh, Ajay Gupta, Puja Prasad, Pritam Mahawar, Shalini Gupta and Pijus K. Sasmal, Inorg. Chem. 2021, 60, 12644–12650.
- Simultaneous Ultrasensitive Detection and Elimination of Drug-Resistant Bacteria by Cyclometalated Iridium(III) Complexes, Ajay Gupta, Puja Prasad, Shalini Gupta and Pijus K. Sasmal, ACS Appl. Mater. Interfaces 2020, 12, 35967–35976
