M. J. Swamy
Professor, FNASc, FASc 
Ph. D. IISc, Bangalore, 1987
Postdoctoral Research    Michigan State University, 1987 - 1989   

Max-Planck Institut für biophysikalische Chemie, 1990 - 1993
Assistant Professor University of Hyderabad, 1993 - 1998
Associate Professor University of Hyderabad, 1998 - 2004
Professor University of Hyderabad, 2004 - Present  
   
Phone: +91- 40- 23134807, E-mail: mjswamy@uohyd.ac.in 
Research Interests 
  • Phase behavior and polymorphism of lipids 
  • Biomembrane structure and function 
  • Protein chemistry and structure 
  • Protein-ligand interactions  
In the pursuit of the above areas of research, a variety of techniques are used including protein purification and characterization methods, differential scanning calorimetry (DSC), spin-label ESR spectroscopy, 31P-NMR spectroscopy, isothermal titration calorimetry (ITC), CD spectroscopy, absorption and fluorescence spectroscopy, nuclear magnetic resonance spectroscopy, single-crystal X-ray diffraction, small-angle X-ray scattering and Langmuir film balance measurements.
Selected Publications
  • Coccinia indica Agglutinin, a 17 kDa PP2-Like Phloem Lectin: Affinity Purification, Primary Structure and Characterization of Self-Assembled Filaments. K. B. Bobbili, G. Pohlentz, A. Narahari, K. Sharma, A. Surolia, M. Mormann and M. J. Swamy, Int. J. Biol. Macromol. (2018) 108, 1227-1236. 
  • Spermine and Spermidine Act as Chemical Chaperones and Enhance Chaperone-Like and Lipid Binding Activities of Bovine Seminal Plasma Protein, PDC-109. B. P. Singh, I. Saha, I. Nandi and M. J. Swamy, Biochem. Biophys. Res. Commun. (2017) 493, 1418-1424. 
  • A pH Switch Regulates the Inverse Relationship Between Membranolytic and Chaperone-Like Activities of HSP-1/2, a Major Protein of Horse Seminal Plasma. C. S. Kumar and M. J. Swamy, Biochemistry (2016) 55, 3650-3657. 
  • Self-assembly, Supramolecular Organization and Phase Behavior of L-Alanine Alkyl Esters (n = 9-18) and Characterization of Equimolar L-Alanine Lauryl Ester/Lauryl Sulphate Catanionic Complex. D. Sivaramakrishna and M. J. Swamy, Langmuir (2015) 31, 9546-9556.
  • Structure and Thermotropic Phase Behavior of a Homologous Series of N-Acylglycines: Neuroactive and Antinociceptive Constituents of Biomembranes. S. T. Reddy, K. P. Krovi and M. J. Swamy, Cryst. Growth Des. (2014) 14, 4944-4954.
  • Effect of Hofmeister Series Anions on the Thermotropic and Chaotropic Phase Behavior of Bioactive O-Acylcholines.  
    P. K. Tarafdar, S. T. Reddy and M. J. Swamy, J. Phys. Chem. B. (2013) 117, 9900-9909. 
  • Nonclassical Odd-even Alternation in Mixed-chain Diacylethanolamines: Implications of Polymorphism.  
    P. K. Tarafdar, S. T. Reddy and M. J. Swamy, Cryst. Growth Des. (2012) 12, 1132-1140. 
  • Isothermal Titration Calorimetric and Computational Modeling Studies on Chitooligosaccharide Binding to Pumpkin (Cucurbita maxima) Phloem Exudate Lectin. A. Narahari, H. Singla, G. Bulusu, P. K. Nareddy, A. Surolia and M. J. Swamy, J. Phys. Chem. B. (2011) 115, 4110-4117.
  • The Major Protein of Bovine Seminal Plasma, PDC-109 Is a Molecular Chaperone.  
    R. S. Sankhala and M. J. Swamy, Biochemistry (2010) 49, 3908-3919. 
  • Biophysical Investigations on the Aggregation and Thermal Unfolding of HarpinPss and Identification of Leucine-Zipper-Like Motifs in Harpins. P. K. Tarafdar, V. L. Vasudev, A. Kondreddy, A. R. Podile and M. J. Swamy, Biochim. Biophys. Acta (2009) 1794, 1684-1692.