D. B. Ramachary
Professor
| Ph. D. | IISc, Bangalore, 2001 |
| Skaggs Postdoctoral Research | The Scripps Research Institute, La Jolla, 2002 - 2005 |
| Assistant Professor | University of Hyderabad, 2005 - 2007 |
| Associate Professor |
University of Hyderabad, 2007 - 2013 |
| Professor | University of Hyderabad, 2013 - Present |
Phone: +91- 40- 23134816, E-mail: ramsc@uohyd.ac.in
Research Interests
Chemical synthesis plays an increasingly significant role in the advancement of life sciences. Our research aims to advance this important paradigm. The main emphasis of our group is involved in a wide variety of research including: Developing new green synthetic asymmetric methods and catalysts. The parallel objective is to bring together green catalysis and engineering of new asymmetric reactions in order to enable the development of an arsenal of new small-molecule agents for pharmaceutical research.
Stereoselective synthesis of new carbon-carbon and carbon-hetero atom bond-forming reactions has always been the cynosure in organic synthesis and especially, organo-catalytic cascade or multi-component reactions has fueled the passion for accelerated and greener processes.
Selected Publications
- Discovery of 2-Aminobuta-1,3-enynes in Asymmetric Organocascade Catalysis: Construction of Drug-like Spirocyclic Cyclohexanes having Five to Six Contiguous Stereocenters, Ramachary, D. B.; Venkaiah, Ch.; Krishna, P. M., Chem. Commun. 2012, 48, 2252.
- Asymmetric Supramolecular Catalysis: A Bio-Inspired Tool for the High Asymmetric Induction in the Enamine-Based Michael Reactions, Ramachary, D. B.; Sakthidevi, R.; Shruthi, K. S., Chem. Eur. J. 2012, 18, 8008.
- Asymmetric Synthesis of Druglike Six-Membered Spirooxindoles through an Amino Enyne Catalysis, Ramachary, D. B.; Venkaiah, Ch.; Madhavachary, R., Org. Lett. 2013, 15, 3042.
- An Enolate-Mediated Organocatalytic Azide–Ketone [3+2]-Cycloaddition Reaction: Regioselective High-Yielding Synthesis of Fully Decorated 1,2,3-Triazoles, Shashank, A. B.; Karthik, S.; Madhavachary, R.; Ramachary, D. B., Chem. Eur. J. 2014, 20, 16877.
- An Organocatalytic Azide–Aldehyde [3+2] Cycloaddition: High-Yielding Regioselective Synthesis of 1,4-Disubstituted 1,2,3-Triazoles, Ramachary, D. B.; Shashank, A. B.; Karthik, S., Angew. Chem. Int. Ed. 2014, 53, 10420.