Abani K. Bhuyan
Ph. D. University of Pennsylvania, 1995
Visiting Fellow Tata Institute of Fundamental Research, 1995 - 1999   
Institute of Genomics and Integrative Biology, 2000
Assistant Professor University of Hyderabad, 2000 - 2004
Associate Professor University of Hyderabad, 2004 - 2006
Professor University of Hyderabad, 2006 - Present  
Phone: +91- 40- 23134810, E-mail: akbsc@uohyd.ac.in 
Research Interests 
The protein molecule in solution is a beautiful but complex world by itself. Weak forces of interatomic interactions, structural organization within, and varieties of relaxation dynamics offer a plethora of problems. Equally puzzling is the act of structure acquisition starting from the nascent polypeptide chain. We study these problems using NMR spectroscopy, stopped-flow and laser-based kinetics, and computer modeling and analyses. Currently, we are at the verge of completing the NMR solution structure of Arabidopsis thaliana Phloem Protein 16 (AtPP16), which putatively delivers mRNA in plants. Other ongoing work includes equilibrium thermodynamics and kinetics of protein folding, internal friction in proteins, structure and enzymic function of eukaryotic ribosomal protein S4, and intraprotein energy dissipation response to an impulse. 

Selected Publications
  • Viscosity Dependence of Some Protein and Enzyme Reaction Rates: Seventy-Five Years after Kramers, Sashi, P. and Bhuyan, AK. Biochemistry, 2015, 54, 4453. 
  • Expansion and Internal Friction in Unfolded Protein Chain, Yasin, UM., Sashi, P. and Bhuyan, AK., J. Phys. Chem. B. 2013, 117, 12059.
  • On the Mechanism of SDS-Induced Protein Denaturation, Bhuyan, AK., Biopolymers, 2010, 93, 186.
  • Complexity of Aromatic Ring-Flip Motions in Proteins: Y97 Ring Dynamics in Cytochrome c Observed by Cross-Relaxation Suppressed Exchange NMR Spectroscopy, Rao, DK. and Bhuyan AK, J. Biomol. NMR, 2007, 37, 187.
  • Protein Stabilization by Urea and Guanidine Hydrochloride, Bhuyan, AK Biochemistry, 2002, 41, 13386.