Title: Cu(OTf)2/HFIP Catalyzed Regioselective Cycloisomerization of Indole-C3-functionalized Alkynols to Carbazoles
| Author(s) | Srinivasarao Yaragorla,* T. Khan and S Chakroborty |
|---|---|
| Publication Year | 2024 |
| Journal Name | Org. Biomol. Chem., 2024 |
| Publication Link | https://pubs.rsc.org/en/content/articlelanding/2024/ob/d4ob00421c |
| Short Description | We report here a simple and atom economic cycloisomerization reaction of indole-tethered alkynols for constructing diverse carbazoles using Cu(OTf)2/HFIP as the excellent promoter system. The reaction proceeds through a one-pot, domino process of spiro cyclization and 1,2-migration followed by aromatization to deliver carbazoles |