| Author(s) | Srinivasarao Yaragorla, Garima Singh, Ravikrishna Dada |
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| Publication Year | 2016 |
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| Journal Name | Tetrahedron Lett. 2016, 57, 591-594 |
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| Publication Link | https://www.sciencedirect.com/science/article/pii/S0040403915305116 |
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| Short Description | A catalyst-free and green approach of sp3 C–H functionalization of methyl azaarenes with malononitrile and isatins for the synthesis of oxindole derivatives bearing quaternary carbon center has been described in water. This one-pot three component synthesis endures the key features like first ‘on water synthesis’, short reaction times, moderate to good yields, and large substrate scope. |