Title: nBu4NPF6 Promoted Regioselective Cascade Synthesis of Functionally Embellished Naphthofurans under Acid, Metal & Solvent Free Conditions

Author(s)Abhishek P, Ravikrishna D, Monika R, Anuj K. S, and Srinivasarao Yaragorla
Publication Year2016
Journal NameRSC Adv, 2016, 6, 89732
Publication Linkhttps://pubs.rsc.org/en/Content/ArticleLanding/RA/2016/C6RA17411F#!divAbstract
Short Descriptionn Bu4NPF6 mediated highly regioselective synthesis of functionally embellished naphthofurans has been achieved from easily available naphthols and propargyl alcohols through a cascade benzylation, oxacyclisation (5-exo dig) and isomerization under solvent free conditions. The reaction works in a short time through dibenzyl ether formation followed by the decomposition to the carbocation to furnish the high yielding products with large substrate scope. The synthetic utility of the products is demonstrated through C(sp3)–H functionalization

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