Publication Details:

Title: Ruthenium‐Catalyzed Hydroarylation and One‐Pot Twofold Unsymmetrical C− H Functionalization of Arenes

Author(s)	Koushik Ghosh, Raja K Rit, E Ramesh, Akhila K Sahoo : Angew. Chem. Int. Ed., 2016, 55 , 7821-7825
Journal Name	Angewandte Chemie International Edition
journal image URL	http://chemistry.uohyd.ac.in/~aks/wp-content/uploads/koushikangew_cover.png

More Details:

A methyl phenyl sulfoximine (MPS) is used as a directing group in the ruthenium‐catalyzed intramolecular hydroarylation of alkene‐tethered benzoic acid derivatives to afford dihydrobenzofurans and indolines in good to excellent yields. A one‐pot, unsymmetrical, twofold C−H functionalization involving intramolecular C−C and intermolecular C−C/C−N bond formations is successfully demonstrated by using a single set of catalytic reaction conditions, which is unprecedented thus far. A novel isoquinolone‐bearing dihydrobenzofuran is constructed through an unsymmetrical twofold C−H functionalization.

https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201600649