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Publication Details:

Title: Reusable directing groups [8-aminoquinoline, picolinamide, sulfoximine] in C (sp3)–H bond activation: present and future

Author(s)Raja K Rit, M Ramu Yadav, Koushik Ghosh, Akhila K Sahoo: Tetrahedron Volume 71, Issues 26–27, 1 July 2015, Pages 4450-4459
Journal NameTetrahedron (invited review)
journal image URLhttp://chemistry.uohyd.ac.in/~aks/wp-content/uploads/rajatetrahedron_cover.png

More Details:


This report briefly discusses the reusable directing group assisted functionalization of unactivated remote alkyl C–H bonds and their synthetic potential in organic chemistry. The challenges involved for the functionalization of inert alkyl C–H bonds is highlighted. With the strong impact of C–H activation, we believe this report would boost researchers unraveling novel methods for the chemo-, regio-, and stereoselective activation of unbiased C(sp3)–H bonds and their potential utility for the rapid synthesis of complex molecular entities.

https://www.sciencedirect.com/science/article/pii/S004040201500424X