Publication Details:

Title: Cyclization and Cycloisomerization of π-Tethered Ynamides: An Expedient Synthetic Method to Construct Carbo-and Heterocycles

Author(s)	B Prabagar, Nayan Ghosh, Akhila K Sahoo : Synlett, 2017, 28, 2539-2555 (Invited Review).
Journal Name	Synlett
journal image URL	http://chemistry.uohyd.ac.in/~aks/wp-content/uploads/prabareview.png

More Details:

Stable ynamides are used for the development of novel synthetic transformations and the construction of unusual carbo/heterocycles. The intramolecular cyclization of π-tethered alkene/alkyne/allene-ynamides is studied extensively for the fabrication of a wide range of molecular scaffolds for various applications. The ketene-acetal/aminal generated in situ from π-tethered ynamides participates in intramolecular cyclization/cycloisomerization processes to yield N-bearing fused heterocycles. This account summarizes the scientific merits and the advances made in cyclization and cycloisomerization strategies for stable π-tethered alkene/alkyne/allene-ynamides.

https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0036-1590877