Publication Details:
Title: Silver-mediated oxidative annulation of N-arylthio succinimides with alkynes: direct access to benzo [b] thiophenes
| Author(s) | E Ramesh, Majji Shankar, Suman Dana, Akhila K Sahoo : Organic Chemistry Frontiers, 2016, 3, 1126-1130 |
|---|---|
| Journal Name | Organic Chemistry Frontiers |
| journal image URL | http://chemistry.uohyd.ac.in/~aks/wp-content/uploads/rameshcover.png |
More Details:
A convenient synthetic route to 2,3-diarylbenzo[b]thiophene derivatives via Ag-catalyzed intermolecular oxidative cyclization between bench-stable N-arylthio succinimides and unactivated internal alkynes is demonstrated herein. The reaction indicates a broad scope, facilitating the construction of diverse arrays of π-conjugated 2,3-diaryl substituted benzothiophenes. The method involves oxidative cleavage of the S–N bond and annulation of alkynes with the concurrent 1,2-S-migration to yield benzo[b]thiophenes.
https://pubs.rsc.org/en/content/articlelanding/2016/qo/c6qo00259e