Dr. Nayan Ghosh
Alumni-Doctoral
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E-mail :nayan.ghosh@cdri.res.in
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Graduation :Hooghly Mohsin college, Burdwan University, West Bengal
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Post Graduation :IIT-Kharagpur, West Bengal, India
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PhD Tenure :Jan, 2009 to May, 2014
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PhD Thesis :A New Avenue for Gold-Catalyzed Hydration of Propagyl Acetates and Hydrative Cyclization of Yne-Tethered Ynamides: Synthesis of N-Heterocycles
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Postdoc Details :ICSN-CNRS, France (with Dr. Angela Marinetti) (Oct.2014 - Oct.2015) and University of Starsbourg, France (With Dr. Gaelle Blond) (Nov.2015 - May.2017)
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Current Position :Senior Scientist & Assistant Professor, Medicinal and Process Chemistry Division, CSIR-CDRI, Lucknow, India
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Research Interests :1) Lewis/π-Acid Catalysis for the synthesis of novel N-heterocycles, 2)Exploration of Alkyne chemistry for novel reaction development, 3)Green synthetic approaches for biologically relevant Heterocycles
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Hobbies :Playing cricket, travelling
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More Details :Dr.Nayan Ghosh was born in Hooghly district of West Bengal, India in 1985. He obtained his bachelor degree in chemistry from Hooghly Mohsin college, West Bengal in 2006. After completing his M.Sc. in chemistry form IIT-Kharagpur in 2008, he joinedtoProf. A. K. Sahoo’s group at the University of Hyderabad for his doctoral studies in 2008. In Prof.Sahoo’s group, his research work focused on the development of novel synthetic methods in yne-tethered ynamides and propargyl acetates applying gold catalyst. After obtaining Ph.D. in 2014, he moved to France forpostdoctoral research at ICSN-CNRS (with Dr. Angela Marinetti) and the University of Strasbourg (with Dr.Gaelle Blond), respectively. After spending two and half year in France, he came back to India and joined as a scientist at CSIR-Central Drug Research Institute, Lucknow in February 2018. At CDRI, his primary research interest is to develop synthetic methodology, leading to organic scaffolds relevant in medicinal chemistry.
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Publications :
7. Cyclization and Cycloisomerization of π-Tethered Ynamides: An Expedient Synthetic Method to Construct Carbo- and HeterocyclesB. Prabagar, N. Ghosh, and Akhila K. Sahoo∗ Synlett 2017, 28, 19, 2539-2555.
6. Ag(I)-Catalyzed Cycloisomerization and Cyclization of Ketene Aminals: Construction of Azepine and 1,2-Dihydropyridine DerivativesS. Nayak, B. Prabagar, N. Ghosh, R. K. Mallick and Akhila K. Sahoo∗ Synthesis 2017, 49, 18, 4261-4271.
5. p-TsOH Promoted Au(I)-Catalyzed Consecutive Endo Cyclization of Yne-Tethered Ynamide: Access to Benzofused DihydroisoquinolonesS. Nayak, N. Ghosh, B. Prabagar, and Akhila K. Sahoo∗ Org. Lett., 2015, 17, 5662.
4. Access to Cyclobutene-Fused Azepines through Au-Catalyzed Cycloisomerization of Stable Alkyne Tethered Ketene N,N-AcetalsS. Nayak, N. Ghosh, and Akhila K. Sahoo∗ Org. Lett., 2014, 16, 2996-2999.
3. Synthesis of a-acyloxy-a′-halo ketones through gold-catalyzed hydration of halo-propargyl acetateN. Ghosh, S. Nayak, B. Prabagar and Akhila K. Sahoo∗ J. Org. Chem. 2014, 79, 2453-2462.
2. Gold(I)-Catalyzed 6-endo-dig Hydrative Cyclization of Alkyne-Tethered-Ynamide: Access to 1,6-Dihydropyridin-2(3H)-onesN. Ghosh, S. Nayak, and Akhila K. Sahoo∗ Chem.-Eur. J. 2013, 19, 9428-9433.
1.Gold-Catalyzed Regioselective Hydration of Propargyl Acetates Assisted by Neighboring Carbonyl Group: Access to α-Acyloxy Methyl Ketones and Synthesis of Actinopolymorphol BN. Ghosh, S. Nayak, and Akhila K. Sahoo∗ J. Org. Chem. 2011, 76, 500-511.