Text Box:  Publications
Journal home page for Journal of Biological ChemistryGo to Organic Letters TetrahedronGraphical abstract: A facile access to substituted benzo[a]fluorenes from o-alkynylbenzaldehydes via in situ formed acetalsGo to The Journal of Organic Chemistry Go to Organic Letters Graphical abstract: The directing group wins over acidity: kinetically controlled regioselective lithiation for functionalization of 2-(2,4-dihalophenyl)-1,3-dithiane derivativesGraphical abstract: Gold-catalysed glycosylation reaction using an easily accessible leaving groupimageimageGo to Organic Letters Abstract ImageimageimageimageAbstract ImageimageimageimageGraphical abstract: Catalyst free synthesis of α-fluoro-β-hydroxy ketones/α-fluoro-ynols via electrophilic fluorination of tertiary propargyl alcohols using Selectfluor™ (F-TEDA-BF4)Graphical abstract: In situ formed acetals facilitated direct Michael addition of unactivated ketonesimageAbstract ImageGraphical abstract: TfOH-promoted synthesis of indoles and benzofurans involving cyclative transposition of vinyl ketoneGo to The Journal of Organic Chemistry Figure 1

53

Ag(I)-catalyzed cyclization of o-alkynylacetophenones facilitated through acetal formation: synthesis of C3-naphthyl indole derivatives

G. Ramesh, V. Srivardhan and R. Balamurugan

Org. Biomol. Chem., 2022  DOI: 10.1039/D2OB01873J 

 

52

Activation of o-Propargyl Alcohol Benzaldehydes under Acetalization Conditions for Intramolecular Electrophile Intercepted Meyer–Schuster Rearrangement.

G. Ramesh, B. V. Ramulu and R. Balamurugan

J. Org. Chem. 2022, 87, 13, 8633–8647.

 

51

TfOH-promoted synthesis of indoles and benzofurans involving cyclative transposition of vinyl ketone

M Mandal and R Balamurugan

Chem. Commun., 2022, 58, 9778–9781.

 

50

Triflic Acid-Catalyzed Synthesis of Indole-Substituted Indane Derivatives via In Situ Formed Acetal-Facilitated

Nucleophilic Addition and 4π-Electron-5-Carbon Electrocyclization Sequence

G. Ramesh, and R. Balamurugan

J. Org. Chem. 2021, 86, 16278-16292.

 

 

 

 

49

Synthesis of Highly Substituted Biaryls by the Construction of a Benzene Ring via In Situ Formed Acetals

C. Tarigopula, S. Manojveer, and R. Balamurugan

J. Org. Chem. 2021, 86, 11871-11883.

 

48

Brřnsted/Lewis Acid-Promoted Site-Selective Intramolecular Cycloisomerizations of Aryl-Fused 1,6-Diyn-3-ones for DiversityOriented Synthesis of Benzo-Fused Fluorenes and Fluorenones and Naphthyl Ketones

M. Mandal, S. Sakthivel, and R. Balamurugan

J. Org. Chem. 2021, 86, 333-351.

 

47

Synthetic homoserine lactone analogues as antagonists of bacterial quorum sensing

X. Qin, G. K. Thota, R. Singh,* R. Balamurugan,* F. M. Goycoolea*

Bioorg. Chem. 2020, doi.org/10.1016/j.bioorg.2020.103698

 

46

Reversible Addition of Cyanide to Triphenylamine Attached Difluoroboron b-Diketonate Facilitated Selective Colorimetric and Fluorimetric Detection of Cyanide Ion

D. Tamilarasan, R. Suhasini, V. Thiagarajan* and R. Balamurugan*

Eur. J. Org. Chem. 2020, 993-1000.

 

45

Silver‐Catalyzed Synthesis of Enones/α‐Iodoenones from Tertiary Propargyl Alcohols

N. Naveen, G. Ramesh and R. Balamurugan

ChemistrySelect 2019, 4, 13610–13614.

 

44

Efficient Sensing of Trinitrotoluene Using a Photoluminescent Benzo[a]fluorenone Derivative

M. Mandal and R. Balamurugan

ChemistrySelect 2019, 4, 10164–10168.

 

43

Annulation of a Highly Functionalized Diazo Building Block with Indoles Under Sc(OTf)3/Rh2(OAc)4 Multicatalysis Through Michael Addition/Cyclization Sequence

S. Sakthivel and R. Balamurugan

J. Org. Chem. 2018, 83, 12171-12183.

 

42

TfOH-Mediated Expedient Synthesis of Benzo[a]fluorenes and Fluorescent Benzo[a]fluorenones

M. Mandal and R. Balamurugan

Adv. Synth. Catal. 2018, 360, 1453-1465.

 

41

Synthesis of Highly Functionalized Pyrrolidine Derivatives from Easily Accessible Diethyl (E)-4-Oxohex-2-enedioate

G. K. Thota, D. Tamilarasan and R. Balamurugan

Eur. J. Org. Chem. 2017, 6417-6426.

 

40

Silver Catalyzed Synthesis of Substituted Pyridine Derivatives from N-Propargylic α-Enamino Esters

S. Sakthivel, A. Sharma and R. Balamurugan*

Eur. J. Org. Chem. 2017, 3941-3946

 

39

Catalyst free synthesis of α-fluoro-β-hydroxy ketones/α-fluoro-ynols via electrophilic fluorination of tertiary propargyl alcohols using SelectfluorTM(F-TEDA-BF4)V

Naganaboina Naveen and Rengarajan Balamurugan*

Org. Biomol. Chem. 2017, 15, 2063-2072

 

38

In Situ Formed Acetals Facilitated Direct Michael Addition of Unactivated Ketones

S. R. Koppolu and R. Balamurugan*

New. J. Chem. 2017, 41, 1186-1192

 

37

Efficient synthesis of functionalised b-ketoesters and b-diketones via cationic NHC-Au(I) catalysed regioselective hydration of alkynylesters and alkynyl ketones

T. Chandrahas, G. K. Thota and R. Balamurugan*

Eur. J. Org. Chem. 2016, 5855-5861

 

36

Amino groups of chitosan are crucial for binding to a family 32 carbohydrate binding module of a chitosanase from Paenibacillus elgii

S. B. Das, M. Wagenknecht, P. K. Nareddy, B. Bhuvanachandra, R. Niddana, R. Balamurugan, M. J. Swamy, B. Moerschbacher, A. R. Podile*

J. Biol. Chem. 2016, 291, 18977-18990.

 

35

Directing Group Wins Over Acidity: Kinetically Controlled Regioselective Lithiation for Functionalization of 2-(2,4-dihalophenyl-1,3-dithiane Derivatives

S. Sakthivel, R. B. Kothapalli and R. Balamurugan*

Org. Biomol. Chem. 2016, 14, 1670-1679.

 

 

 

34

In Situ Formed Acetal-Facilitated Synthesis of Substituted Indene Derivatives from o-Alkenylbenzaldehydes

S. Manojveer and R. Balamurugan*

Org. Lett. 2015, 17, 3600-3603.

 

 

 

 

33

A Cascade Approach to Naphthalene Derivatives from o-Alkynylbenzaldehydes and Enolizable Ketones via in Situ Formed Acetals

S. Manojveer and R. Balamurugan*

Eur. J. Org. Chem. 2015, 4254-4260.

 

 

 

32

Gold-catalysed glycosylation reaction using an easily accessible activator

S. R. Koppolu, R. Niddana and R. Balamurugan*

Org. Biomol. Chem. 2015, 13, 5094-5097.

 

 

 

 

31

AgSbF6-Catalyzed Direct α-Alkylation of Unactivated Ketones

N. Naveen, S. R. Koppolu and R. Balamurugan*

Adv. Synth. Catal. 2015, 357, 1463-1473.

 

 

 

30

Tandem activation by gold: Synthesis of dioxolanes by intermolecular reaction of epoxides and alkynes in acetone

G. K. Thota, T. Chandrahas and R. Balamurugan*

Tetrahedron 2015, 71, 2280-2289.

 

 

 

29

A Facile Access to Substituted Benzo[a]fluorenes From o-Alkynylbenzaldehydes via In Situ Formed Acetals

S. Manojveer and R. Balamurugan*

Chem. Commun. 2014, 50, 9925-9928.

 

 

 

 

28

Triflic acid Promoted Direct α-Alkylation of Unactivated Ketones Using Benzylic Alcohols via in situ Formed Acetals

S. R. Koppolu, N. Naveen and R. Balamurugan*

J. Org. Chem. 2014, 79, 6069-6078.

 

27

Synthesis of Naphthalene Derivatives from ortho-Alkynylacetophenone Derivatives via Tandem in Situ Incorporation of Acetal and Intramolecular Heteroalkyne Metathesis/Annulation

S. Manojveer and R. Balamurugan*

Org. Lett. 2014, 16, 1712-1715.

 

 

 

 

26

Synthesis of Chiral a-Diarylacetic Esters by Stereospecific 1,2-Aryl Migration Promoted by in Situ Generated Acetals from Benzoins

R. B. Kothapalli, R. Niddana and R. Balamurugan*

Org. Lett. 2014, 16, 1278-1281.

 

 

 

 

25

Synthesis of 1-Arylnaphthalenes by Gold-Catalyzed One-Pot Sequential Epoxide to Carbonyl Rearrangement and Cyclization with Arylalkynes

V. Gudla, R. Balamurugan*

Chem. Asian J. 2013, 8, 414 -428.

 

 

 

 

24

AuCl3/AgSbF6-catalyzed rapid epoxide to carbonyl rearrangement

V. Gudla, R. Balamurugan*

Tetrahedron Lett. 2012, 53, 5243-5247.

 

 

 

 

23

Synthesis of Arylnaphthalene Lignan Scaffold by Gold-Catalyzed Intramolecular Sequential Electrophilic Addition and Benzannulation

V. Gudla and R. Balamurugan*

J. Org. Chem, 2011, 76, 9919-9933.

 

 

 

 

22

Gold/copper-Catalyzed Activation of the Aci-Form of Nitromethane in the Synthesis of Methylene-Bridged Bis-1,3-Dicarbonyl Compounds.

R. Balamurugan,* and S. Manojveer

Chem. Commun. 2011, 47, 11143 -11145.

 

21

Homo and Heterocoupling of Terminal Alkynes Using CuCl2 and DBU

R. Balamurugan,* N. Naveen, S. Manojveer, M. V. Nama,

Aust. J. Chem. 2011, 64, 567-575.

 

20

Gold-Catalysed Activation of Epoxides: Application in the Synthesis of Bicyclic Ketals.

R. Balamurugan,* R. B. Kothapalli, and G. K. Thota

Eur. J. Org. Chem. 2011, 1557-1569.

 

19

Gold-Catalyzed Electrophilic Addition to Arylalkynes. A facile Method for the Regioselective Synthesis of Substituted Naphthalenes.

R. Balamurugan* and V. Gudla

Org. Lett. 2009, 11, 3116-3119.

 

18

Scope of AuCl3 in the Activation of per-O-Acetylglycals.

R. Balamurugan* and S. R. Koppolu

Tetrahedron 2009, 65, 8139-8142.

 

 

 

 

17

Small-Molecule Inhibition of APT1 Affects Ras Localization and Signalling.

F. J. Dekker, O. Rocks, N. Vartak, A. Menninger, C. Hedberg, R. Balamurugan, S. Wetzel, S. Renner, M. Gerauer, B. Schoelermann, M. Rusch, J. W. Kramer, D. Rauh, G. W. Coates, L. Burnsveld, P. I. H. Bastiaens, H. Waldmann

Nature Chem. Biol. 2010, 6, 449-456.

 

16

A Functional Screen Implicates MicroRNA-138-dependent Regulation of the Depalmitoylation Enzyme APT1 in Dendritic Spine Morphogenesis.

G. Siegel, G. Obernosterer, R. Fiore, S. Bicker, M. Christensen, M. Veith, P. F. Leuschner, C. J. L. Busch, C. Kane, K. Huebel, F. Dekker, C. Hedberg, R. Balamurugan, C. Drepper, H. Waldmann, S. Kauppinen, M. E. Greenberg, M. Rehmsmeier, J. Martinez and G. Schratt

Nature Cell Biol. 2009, 11, 705-716.

 

 

15

Nonglycosidic Agonists of Invariant NKT Cells for Use as Vaccine Adjuvants.

B. Gopal Reddy, J. D. Silk, M. Salio, R. Balamurugan, D. Shepherd, G. Ritter, V. Cerundolo, R. R. Schmidt

Chem Med Chem 2009, 4, 171-175.

 

14

b-Lactone Probes Identify a Papain-Like Peptide Ligase in Arabidopsis thaliana.

Z. Wang, C. Gu, T. Colby, T. Shindo, R. Balamurugan, H. Waldmann, M. Kaiser, R. A. L. van der Hoorn

Nature Chem. Biol. 2008, 4, 557-563.

 

13

p-Selectivities of trans-2-Heterobicyclo[4.4.0]decan-5-ones in Reductions with NaBH4 and Na(CN)BH3.

R. Balamurugan, V. Sriramurthy and V. K. Yadav

Ind. J. Chem. 2007, 46B, 509-515.

 

 

12

Distinguishing the Early and Late Transition States and Exploring the Validity of s→s*#, s#→s*, and s→p*C=O Concepts in Diastereoselection from NBO Analysis.

V. K. Yadav, A. Gupta, R. Balamurugan, V. Sriramurthy, and N. Vijaya Kumar

J. Org. Chem. 2006, 71, 4178-4182.

 

11

Design of Compound Libraries Based on Natural Product Scaffolds and Protein Structure Similarity Clustering (PSSC).

R. Balamurugan, F. J. Dekker and H. Waldmann

Mol. Biosyst. 2005, 1, 36-45.

 

 

 

10

Michael-Type Addition to 2-Nitrogalactal-A Simple Method to Access 1,1-Linked Oligosaccharides.

R. Balamurugan, K. Pachamuthu and R. R. Schmidt

Synlett. 2005, 134-138.

 

9

Diasteroselective Aldol Reactions of Enolates Generated from Vicinally Substituted Trimethylsilylmethyl Cyclopropyl Ketones.

V. K. Yadav and R. Balamurugan

Org. Lett. 2003, 5, 4281-4284.

 

8

Bicyclo[2.1.1]hexan-2-one as a New Probe for the Study of p-Facial Selectivity in Nucleophilic Additions. A Comment

V. K. Yadav, K. Ganesh Babu and R. Balamurugan

Tetrahedron Lett. 2003, 44, 6617-6619.

 

7

Synthesis of g-Methylene Oxacycles and a- and b-Alkylidene Lactones via Silicon-Assisted Ring Opening of Cyclopropyl Carbinols

V. K. Yadav and R. Balamurugan

Chem. Commun. 2002, 514-515

 

6

4-Oxa-tricyclo[5.2.1.02,6]decan-10-one and 4-Oxa-tricyclo[5.2.1.02,6]dec-8-en-10-one. Experimental and DFT Investigations of the p-selectivities

V. K. Yadav and R. Balamurugan

J. Org. Chem. 2002, 67, 587-590.

 

5

Silicon-Assisted Ring Opening of Donor-Acceptor Substituted Cyclopropanes. An Expedient Entry to Substituted Dihydrofurans

V. K. Yadav and R. Balamurugan

Org. Lett. 2001, 3, 2717-2719.

 

4

The Thionophosphate-Thiolophosphate Photoisomerization Proceeds Predominantly Through a Non-Chain Radical Pathway. Synthetically Viable Benzylation of Tetrahydrofuran, Propan-2-ol, and Olefins

V. K. Yadav, R. Balamurugan, M. Parvez and R. Yamdagni

J. Chem. Soc., Perkin Trans 1. 2001, 323-332.

 

3

Comparison of the Cieplak Model and the Cation Complexation Model as Applied to Selected 2,3-Disubstituted Norbornan-7-one

V. K. Yadav and R. Balamurugan

J. Chem. Soc., Perkin Trans 2. 2001, 1-2.

 

2

p-Facial Selectivities of Diastereotopic Ketones: p-Bromobenzoates of 4-Hetero-1-decalinols

M. Parvez, V. K. Yadav and R. Balamurugan

Acta Cryst. 2001, C57, 1084-1088.

 

1

The Cation Complexation Model Predicts the Experimental p-Facial Selectivity of 2-ax- and 2-eq-Substituted Cyclohexanones. A Detailed Ab Initio MO Investigation

V. K. Yadav, D. A. Jeyaraj and R. Balamurugan

Tetrahedron 2000, 56, 7581-7589.

 

 

Patent

Preparation of a-Galactosylceramide Analogs for Use in the Treatment of a Virus, Microbial Infection, Parasite, an Autoimmune Disease, Cancer, Allergy, or Asthma.

V. Cerundolo, R.R. Schmidt, G. Reddy, R. Balamurugan, G. Ritter, G. Besra, M. Salio, J.Silk

US8334408, US8188313, US8039670, CN101331146