Publication Details:

Title: Gold-Catalyzed Transformation of Ynamides

Author(s)	Shashank Shandilya, Manash Protim Gogoi, Shubham Dutta, Akhila K. Sahoo* : DOI: https://doi.org/10.1002/tcr.202100159. The Chemical Record. (invitation)
Journal Name	The Chemical Record
journal image URL	http://chemistry.uohyd.ac.in/~aks/wp-content/uploads/TCR.jpg

More Details:

Ynamide, a unique species with inherited polarization of nitrogen lone pair electron to triple bond, has been largely used for the development of novel synthetic methods and the construction of unusual N-bearing heterocycles. The reaction versatility of ynamide on umpolung reactivity, radical reactions, and asymmetric synthesis have been recently reviewed. This review provides an overall scenic view into the gold-catalyzed transformation of ynamides. The ynamides reactivity towards nitrogen-transfer reagents, such as azides, nitrogen ylides, isoxazoles, and anthranils; oxygen atom-transfer reagents, like nitrones, sulfoxides, and pyridine N-oxides; and carbon nucleophiles under gold catalysis are herein uncovered. The scope as well the mechanistic insights of each reaction is also briefed.

https://onlinelibrary.wiley.com/doi/full/10.1002/tcr.202100159